Scientist- Antibody

Precision Life Sciences - Waltham, MA, United States

We are seeking a skilled scientist with expertise in antibody discovery, engineering, and characterization. This role will report to Senior Director of Antibody. This individual will play a critical role in identifying and optimizing therapeutic antibodies. The successful candidate will be primarily lab-based and will be a member of project teams; he/she may also interact with CRO partners and contribute to strategic decision-making.

Job Responsibilities

  • Design, construct, and screen antibody libraries to identify or optimize antibodies with desired properties
  • Characterize antibodies biophysically
  • Work closely with Biology group to ensure fast advancement of programs
  • Communicate/present data in group and project team meetings
  • Document work in a timely fashion in electronic lab notebook

Qualifications And Education Requirements

  • BS with 5+, MS with 3+ years of industry experience, or PhD in a closely related field. Title is commensurate with experience.
  • Hands-on experience in yeast display and/or phage display required
  • Experience in antibody affinity maturation, humanization, etc.
  • Experience in antibody biophysical characterization methods such as ELISA, binding kinetics and binning by Octet/SPR, flow cytometry, DSF, etc.
  • Experience with alternative antibody formats, such as single-domain or bi-specific antibody is desired
  • Comprehensive knowledge in therapeutic antibody development
  • Ability to work independently with minimal guidance to design, execute, interpret, and troubleshoot experiments
  • A team player with excellent verbal and written communication skills, ability to thrive in a fast-paced environment


Posted On: Monday, November 11, 2024



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