Scientist- Antibody
Precision Life Sciences
- Waltham, MA, United States
We are seeking a skilled scientist with expertise in antibody discovery, engineering, and characterization. This role will report to Senior Director of Antibody. This individual will play a critical role in identifying and optimizing therapeutic antibodies. The successful candidate will be primarily lab-based and will be a member of project teams; he/she may also interact with CRO partners and contribute to strategic decision-making.
Job Responsibilities
- Design, construct, and screen antibody libraries to identify or optimize antibodies with desired properties
- Characterize antibodies biophysically
- Work closely with Biology group to ensure fast advancement of programs
- Communicate/present data in group and project team meetings
- Document work in a timely fashion in electronic lab notebook
Qualifications And Education Requirements- BS with 5+, MS with 3+ years of industry experience, or PhD in a closely related field. Title is commensurate with experience.
- Hands-on experience in yeast display and/or phage display required
- Experience in antibody affinity maturation, humanization, etc.
- Experience in antibody biophysical characterization methods such as ELISA, binding kinetics and binning by Octet/SPR, flow cytometry, DSF, etc.
- Experience with alternative antibody formats, such as single-domain or bi-specific antibody is desired
- Comprehensive knowledge in therapeutic antibody development
- Ability to work independently with minimal guidance to design, execute, interpret, and troubleshoot experiments
- A team player with excellent verbal and written communication skills, ability to thrive in a fast-paced environment
Posted On: Monday, November 11, 2024