Senior Manager, Global Program Management (Contract to Hire)

Precision Life Sciences - Cambridge, MA


  • Provides global program management to global, cross-functional, cross-divisional teams to drive development and deliver results in early to late-phase pipeline or marketed assets.
  • The remit includes providing strategic direction and translating the cross-divisional, integrated Global Product Team (GPT) strategy into an efficiently executable plan; predicting and planning solutions to achieve program goals and objectives; driving clarity and removing barriers to ensure team success; interfacing with management and influencing decision-making, proactive management and mitigation of development risks, and ensuring appropriate communication and interface with internal governance.
  • Works closely with the Global Program Leader (GPL), as well as other Chief Medical Scientific Officer (CMSO) and Commercial functions to ensure that the scientific and commercial strategies are incorporated into the asset strategy and integrated development plan.
  • May lead key initiatives that have a cross-functional or cross-divisional impact that is critical to the objectives of the Therapeutic Area Unit (TAU), CMSO, and/or global business objectives.

Strategic Direction

  • Partners with GPL to lead GPT or joint Program Team (for partnered Alliance programs) to develop and maintain the asset strategy and integrated development plan in conjunction with TAU and commercial strategy, life-cycle management requirements, and evidence generation/publication needs.
  • Proactively identifies resource requirements necessary to progress asset development in alignment with TAU or enterprise business objectives.
  • Drives clarity with GPT and other relevant stakeholders to communicate asset strategic imperatives to ensure appropriate prioritization.

Program Execution

  • Identifies ways to optimize program execution without compromise to patients or compliance.
  • Accountable to maintain the integrated program level plan, ensuring delivery of critical path activities to progress asset development.
  • Program Operational Excellence
  • Ensures asset strategy and integrated development plan have a patient-centric focus,
  • incorporates innovative approaches that are meaningful to patients, HCPs, regulators & payers, and adhere to the highest standards of operational excellence in drug development and life cycle management.
  • Manages the strategic GPT forum to ensure the progress of asset development. This includes establishing meeting agendas, facilitating team discussions, and driving to clear and timely team actions and decisions.
  • Partners with the GPL to provide financial oversight of the program including global, cross-divisional budgets. Includes consolidation, vetting, and prioritization of GPT spending to deliver critical path activities.

Risk Management

  • Proactively addresses and removes barriers to program progress, keeping leadership informed of critical considerations (e.g., resources, performance).
  • Proactively identify potential issues or obstacles and achieves resolution or plans contingencies. Follow issues through to resolution ensuring that all key stakeholders are informed of outcomes and program implications.
  • Provides clarity and direction in urgent or unexpected situations. Independently resolves complex issues and competing priorities that may impact the achievement of goals, creates mitigation plans, and drives to resolution.

Communication and Reporting

  • Manages scheduled and ad-hoc program status reporting, citing progress to program goals/KPIs, proactively identifying risk with planned mitigation(s), and providing a rationale for the timeline and budget variances.
  • Participate in annual portfolio analyses to communicate program development progress, opportunities, and risks to Senior & Executive Management.
  • Responsible for leading preparation efforts for governance engagement to support and drive asset objectives and deliverables.
  • Facilitates relevant communications to appropriate cross-regional, cross-functional, cross-divisional, and Alliance partners.


  • Bachelor’s Degree science or business-related field
  • Advanced degree in science or business is preferred


  • Significant pharmaceutical industry experience and drug development in all phases of development with significant experience within related functions (e.g. Clinical Science, Clinical Operations, Research, Regulatory, CMC, Marketing)
  • Relevant project management experience in drug development related field
  • Demonstrated ability to positively influence outcomes, key project decisions, and strategic problem-solving
  • Proven ability to communicate clearly and present key information objectively to all levels of the organization

Knowledge And Skills

  • Ability to influence and negotiate in a matrix environment to optimize development and address barriers
  • Proactive risk management with the ability to propose solutions and deliver appropriate mitigation plan
  • Ability to communicate with impact to provide appropriate context, articulate views, drive clarity, and address barriers to progress program development
  • Ability to drive decision-making within a cross-functional and cross-cultural, global team structure
  • Flexibility, tolerance, and diplomacy to best manage change and differing opinions
  • Ability to work in a virtual setting/across time zones, i.e., making effective use of communication tools (WebEx, TelePresence, telephone and video conferencing, etc.)
  • Ability to inspire and motivate in a matrix and global, cross-geographical team
  • Ability to work in a highly complex, multi-cultural, environment
  • Excellent organizational skills


Posted On: Wednesday, July 20, 2022

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