Scientist: Protein Biochemistry

Terray Therapeutics - Pasadena, CA

Company Overview: Terray Therapeutics is a venture backed biotechnology company utilizing a novel spatially encoded screening and optimization platform to develop treatments for historically intractable causes of human disease. The Company's platform technology has the industry’s highest throughput capacity, broadest target applicability and most comprehensive data output.Our internal development programs are focused on oncology and immunology. In addition to these programs we also work with leading pharmaceutical companies. Our platform is based on fluorescent imaging of ultra-dense microarrays such that we can measure billions of target/molecule interactions in a day, generating hundreds of millions of dose-response binding curves.

Position Summary: The scientist will be responsible for design, planning and generation of key enabling reagents to support early discovery of small molecule therapeutics. This involves identifying the most productive labelling strategies for a wide variety of proteins, evaluating the feasibility of screening different protein classes, as well as working alongside talented associate scientists to perform hands-on protein conjugation, purification and biochemical characterization for a variety of protein classes. Identifying optimal buffers for functionalized proteins is also key. The scientist will not only lead the team preparing these reagents but also lead screening these reagents using Terray’s cutting edge platform.

The scientist will also be responsible for design, planning and execution of follow-up biochemical, cellular and animal studies for potent hits that are identified. This follow-up work will be conducted both onsite and at various CROs.

Experience and Qualifications:


Required Qualifications:

  • PhD in biology, chemistry or related field

    OR

  • Master’s degree in biology, chemistry or related field and 4 years of related experience
  • Broad training in protein biochemistry
  • Familiarity with fluorescent microscopy
  • Experience with in vitro biochemical and cellular assays.
  • Proficiency in protein purification methods including experience with chromatography instrumentation such as HPLC, FPLC and/or LC-MS
  • Understanding of and hands-on experience with common strategies for protein labelling.
  • Strong written and verbal communication and interpersonal skills.


    Preferred Qualifications:

  • Familiarity with animal models of disease
  • Experience training/leading RA-level scientists



Given the company’s size, anticipated growth and fast-paced environment, the organization requires a Protein Biochemist who is thoughtful, high energy and can partner with the broader organization to further enhance our next generation drug discovery capabilities.

She/he will exhibit the ability to work well under pressure to provide results in a short timeframe. The company is looking for a highly responsive, goal-oriented individual who will bring significant energy and drive to solve complex technical problems and help us achieve our mission to advance human health.

Part of Terray Therapeutics’ success is nurtured by a hands-on work environment where everyone is accountable, everyone is vested in a vision of excellence, and everyone actively takes part in the success of the business. Terray Therapeutics supports a positive work environment comprised of engaged employees who feel appreciated, recognized and free to be creative.



Posted On: Thursday, September 26, 2019



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